Fluid Mechanics in Bioreactors and Fermentation

Picture from: https://www.kt.dtu.dk/english/Research/PROSYS

Wednesday 25th of May 2022, DTU and DANSIS will host a seminar on Fluid Mechanics in Bioreactors and Fermentation. The event is co-arranged by DTU Chemical Engineering’s PROSYS research center.

Bioreactors and fermentation are widely used to transform raw materials to products with the aid of living organisms. Examples are many and include food, beverages, pharmaceuticals, enzymes for cleaning, biofuels, and treatment of wastewater.

Bioreactors and fermentation have been around for a long time and are becoming even more widespread. They contribute to combatting climate change, by creating biofuels and food with reduced CO2 impact. Bioreactors also contribute to keep the world’s population healthy by creating vaccines and other medicines.

In bioreactors and fermentation, many different technology disciplines are required to merge, for example biology, chemistry, and fluid mechanics. The sector is typically interested in the process impact by phenomena such as mixing, heat transfer, two phase flow, bubble break up, mass transfer, process gradients and effects of shear forces.

Among other topics, we will hear about fermentation, membrane filtration and how 3D modelling is coupled with transient system simulations. We will hear about measurements, experiments, and modelling. Furthermore, PROSYS invites us for a short visit of their lab facilities.

From the industry, we will meet experts from companies including Chr. Hansen, Freesense, Novo Nordisk, and Novozymes.

We look forward to meeting the participants in the new Lounge at:

Chemical Engineering department
DTU building 228A, second floor
2800 Kgs. Lyngby .

Program:

9:00       Registration

9:30       Welcome
Kristian Ingvorsen, GEA, Denmark

9:45       From micro to macro - scale matters (slides)
Ulrich Krühne, Department of Chemical and Biochemical Engineering – PROSYS,
Denmark

10:15     Reducing risk and accelerating bioprocess scale up using computational
 modelling (slides)
Alex Smith, CPI, United Kingdom

10:45     Coffee Break

11:15     Flow following sensor technology, a route to validated fluid dynamic models (slides)
Tannaz Tajsoleiman, Freesense, Denmark

11:45     CFD assisted design of Immiscible Drop Separation System in Micro-channels (slides)
Oscar Andres Pardo Rubio, Department of Chemical and Biochemical Engineering – PROSYS, DTU, Denmark

12:15     Lunch

12:45     Lab tour - Pilot plants and measurement equipment

13:20     Applications of Computational Fluid Dynamics to Industrial Cultivation (slides)
Robert Spann, Chr. Hansen, Denmark

13:50     Accelerating the development of fermenterphiles using scale-down
 bioreactors
Suresh Sudarsan, DTU Biosustain, Denmark

14:10     Making Cell Factories First-Class Citizens in Digital Twins of Bioprocesses (slides)
Nikolaus Sonnenschein, DTU Bioengineering, Denmark

14:35     Break

15:05     Methods to develop and optimize Unibio reactor (slides)
Lisa Mears & Tiago Pinto, Unibio, Denmark

15:35     Closing remarks
Knud Erik Meyer, DANSIS chaiman & DTU, Denmark

15:45     End of Seminar

Members of DANSIS can participate in the seminar free of charge. Non-members are also invited to participate at a fee of 400 DKK.

Please register for the seminar no later than Monday 23nd of May.

Register for the seminar