Fluid Mechanics in Bioreactors and Fermentation

Fluid Mechanics in Bioreactors and Fermentation

Venue:      Chemical Engineering department DTU building 228A, second floor 2800 Kgs. Lyngby

Date:         25 May 2022









DTU and DANSIS will host a seminar on Fluid Mechanics in Bioreactors and Fermentation. The event is co-arranged by DTU Chemical Engineering’s PROSYS research center.

Bioreactors and fermentation are widely used to transform raw materials to products with the aid of living organisms. Examples are many and include food, beverages, pharmaceuticals, enzymes for cleaning, biofuels, and treatment of wastewater.

Bioreactors and fermentation have been around for a long time and are becoming even more widespread. They contribute to combatting climate change, by creating biofuels and food with reduced CO2 impact. Bioreactors also contribute to keep the world’s population healthy by creating vaccines and other medicines.

In bioreactors and fermentation, many different technology disciplines are required to merge, for example biology, chemistry, and fluid mechanics. The sector is typically interested in the process impact by phenomena such as mixing, heat transfer, two phase flow, bubble break up, mass transfer, process gradients and effects of shear forces.

Among other topics, we will hear about fermentation, membrane filtration and how 3D modelling is coupled with transient system simulations. We will hear about measurements, experiments, and modelling. Furthermore, PROSYS invites us for a short visit of their lab facilities.

From the industry, we will meet experts from companies including Chr. Hansen, Freesense, Novo Nordisk, and Novozymes.


09:00 Registration  
09:30 Welcome Kristian Ingvorsen, GEA, Denmark
09:45 From micro to macro - scale matters Ulrich Krühne, Department of Chemical and Biochemical Engineering – PROSYS
10:15 Reducing risk and accelerating bioprocess scale up using computational modelling Alex Smith, CPI, United Kingdom
10:45 Coffee Break  
11:15 Flow following sensor technology, a route to validated fluid dynamic models Tannaz Tajsoleiman, Freesense, Denmark
11:45 CFD assisted design of Immiscible Drop Separation System in Micro-channels Oscar Andres Pardo Rubio, Department of Chemical and Biochemical Engineering – PROSYS, DTU, Denmark
12:15 Lunch  
12:45 Lab tour - Pilot plants and measurement equipme  
13:20 Applications of Computational Fluid Dynamics to Industrial Cultivation Robert Spann, Chr. Hansen, Denmark
13:50 Accelerating the development of fermenterphiles using scale-down bioreactors Suresh Sudarsan, DTU Biosustain, Denmark
14:10 Making Cell Factories First-Class Citizens in Digital Twins of Bioprocesses Nikolaus Sonnenschein, DTU Bioengineering, Denmark
14:35 Break  
15:05 Methods to develop and optimize Unibio reactor Lisa Mears & Tiago Pinto, Unibio, Denmark
15:35 Closing remarks Knud Erik Meyer, DANSIS chaiman & DTU, Denmark
15:45 End of Seminar